Archives for Chemistry Experiments of 23190-16-1

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Synthesis of enantiopure aminocyclopropanes by diastereoselective addition of a chiral amino substituted organozinc carbenoid to alkenes

The synthesis of enantiopure aminocyclopropanes is reported, via direct aminocyclopropanation of alkenes with a zinc carbenoid containing a chiral auxiliary. The methodology was applied to the synthesis of a protected aminocyclopropane present in the immunosuppressant Belactosin A. Georg Thieme Verlag Stuttgart.

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Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare