Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, 3976-69-0, Name is (R)-Methyl 3-hydroxybutanoate, SMILES is C[C@@H](O)CC(OC)=O, belongs to chiral-catalyst compound. In a document, author is Gao, Pan, introduce the new discover, Computed Properties of C5H10O3.
An efficient method for the construction ofgem-difluoroallylsilanes with high enantiomeric excessviaa copper-catalysed defluorosilylation of trifluoromethylated alkenes with silylboronates is described. The key to this high enantioselectivity is the careful selection of NaOH as the base and using a triazolium-based chiral N-heterocyclic carbene (NHC) as a ligand in the presence of a copper catalyst. The reaction conditions are mild, and excellent functional group compatibility is observed. This strategy addresses the limitations of the previously described base-mediated defluorosilylation under transition metal-free conditions, which can lead to erosion of the enantioselectivity. The synthetic utilities of the obtainedgem-difluoroallylsilanes are also presented. Computational and experimental data suggest that the reaction proceeds through the enantioselective insertion of silyl-Cu/NHC species into the double bond of trifluormethyl alkenes and the Cu-mediated beta-F elimination steps.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 3976-69-0 is helpful to your research. Computed Properties of C5H10O3.
Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare