The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.39648-67-4, Name is (R)-4-Hydroxydinaphtho[2,1-d:1′,2′-f][1,3,2]dioxaphosphepine 4-oxide, molecular formula is C20H13O4P. In a Article£¬once mentioned of 39648-67-4, Recommanded Product: 39648-67-4
A Br¡ãnsted acid-catalyzed multicomponent reaction for the synthesis of highly functionalized gamma-lactam derivatives
Br¡ãnsted acids catalyze a multicomponent reaction of benzaldehyde with amines and diethyl acetylenedicarboxylate to afford highly functionalized gamma-lactam derivatives. The reaction consists of a Mannich reaction of an enamine to an imine, both generated in situ, promoted by a phosphoric acid catalyst and a subsequent intramolecular cyclization. The hydrolysis of the cyclic enamine substrate can provide enol derivatives and, moreover, a second attack of the amine on the carboxylate can afford amide derivatives. An optimization of the reaction conditions is presented in order to obtain selectively cyclic enamines that can afford the enol species after selective hydrolysis.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Recommanded Product: 39648-67-4, you can also check out more blogs about39648-67-4
Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare