Category: 141556-45-8

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

General procedure: Under a N2 atmosphere, a mixture of imidazolium salts 1(0.225 mmol), PdCl2 (0.15 mmol), K2CO3 (0.45 mmol) and picolinicacid 2 (0.15 mmol) was stirred in anhydrous THF (2.0 mL) underreux for 12 h. Then the solvent was removed under reducedpressure, and the residue was puried by ash column chroma-tography (SiO2) to give complexes 3 as yellow solids., 141556-45-8

The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Zhang, Zhi-Mao; Gao, Yu-Jue; Lu, Jian-Mei; Tetrahedron; vol. 73; 52; (2017); p. 7308 – 7314;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Finely powdered PdCl2 (177 mg, 1.00 mmol) was suspended in CH3CN (5 mL) and N-benzyldimethylamine (160 muL, 143 mg, 1.05 mmol) were added. The solution was heated to 8O0C with stirring until a clear, orange solution was formed (approx. 20 min). Finely powdered K2CO3 (691 mg, 5.00 mmol) was added and the stirring was continued until palladacycle formation was complete, as indicated by the formation of a canary yellow solution (5-10 min). IMesetaCl (375 mg, 1.10 mmol) was added and the mixture was stirred at 8O0C over 18h. The reaction mixture was filtered and evaporated. The resulting product was purified by column chromatography. Upon application of the product to a pad of silica gel (2.5 x 8 cm) pre-equilibrated with CH2CI2, CH2CI2 (100 mL) was used to elute impurities. The pure NHC-palladacycles were eluted with CH2Cl2-ethylacetate (3:1, vol/vol, 150 mL), and the solvent was evaporated. The products were triturated with hexanes (25 mL). After drying in high vacuum, IMes-Pd(dmba)Cl (555 mg, 96%) was obtained as beige solid. 1H NMR (CDCl3, 400 MHz) delta: 7.10 (s, 2H), 6.99 (s, 2H), 6.83-6.76 (m, 4H), 6.70 (td, J= 7.6, 1.2 Hz, IH), 6.58 (d, J= 7.2, 1.2 Hz, IH), 3.53 (s, 2H), 2.45 (s, 6H), 2.44 (s, 6H), 2.29 (s, 6H), 2.23 (s, 6H). 13C NMR (CDCl3, 100 MHz) delta: 175.6, 149.3, 147.6, 138.3, 138.3, 137.4, 136.2, 133.9, 129.4, 128.7, 123.9, 123.2, 123.0, 121.2, 72.2, 50.0, 21.1, 20.2, 19.8. Anal, calcd for C30H37ClN3Pd (581.51): C, 61.96; H, 6.41; N, 7.23. Found: C, 62.02; H, 6.37; N, 7.40., 141556-45-8

141556-45-8 1,3-Dimesityl-1H-imidazol-3-ium chloride 2734211, achiral-catalyst compound, is more and more widely used in various fields.

Reference£º
Patent; AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH; WO2008/156451; (2008); A1;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

A mixtureof the corresponding azolium salt 1a-f (0.55 mmol), pyridineor 3-chloropyridine (4 g), PtCl2 (133 mg, 0.5 mmol), and fi nelyground anhydrous K2CO3 (345 mg, 2.5 mmol) was heated at80 with vigorous stirring for 16 h. In the obtaining of iodidecomplex 2 and bromide complexes 2d-f, fi nely ground KI(498 mg, 3.0 mmol) or KBr (357 mg, 3.0 mmol), respectively,was added to the reaction mixture together with other reactants.Then, the mixture was cooled to room temperature and dilutedwith CH2Cl2 (15 mL), a precipitate formed was fi ltered off . Thesolution was washed with water (3¡Á5 mL), dried with Na2SO4,and passed through a layer of silica gel (height 1 cm, diameter2 cm). The solvent was evaporated on a rotary evaporator,n-hexane (5 mL) was added to the residue, and the mixture wascooled to ~0 C. The precipitate formed was collected by fi ltration,recrystallized from a mixture of CH2Cl2-n-hexane (1 : 2),and dried in vacuo at 40 for 24 h.

141556-45-8, 141556-45-8 1,3-Dimesityl-1H-imidazol-3-ium chloride 2734211, achiral-catalyst compound, is more and more widely used in various fields.

Reference£º
Article; Chikunov; Ranny; Astakhov; Tafeenko; Chernyshev; Russian Chemical Bulletin; vol. 67; 11; (2018); p. 2003 – 2009; Izv. Akad. Nauk, Ser. Khim.; vol. 67; 11; (2018); p. 2003 – 2009,7;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

Add ligand L2690mg (2.0mmol), copper powder 640mg (10.0mmol), 30 mL of water in a 50mL flask, 60 ~ 70 oil bath, the reaction was stirred for 24 hours, the reaction mixture was cooled to room temperature, filtered, the filter cake was washed 3 times with water, the filter cake dissolved in acetonitrile and filtered to remove unreacted copper powder, the solvent was evaporated under reduced pressure to give 520mg as colorless crystals, a yield of 65%.

141556-45-8, The synthetic route of 141556-45-8 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; China Petroleum & Chemical Corporation Shanghai Research Institute of Petrochemical.; Liu, Bo; Jin, Zhaosheng; Lu, Jiangang; Li, Xianming; Zhou, Haichun; (13 pag.)CN105585584; (2016); A;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The silver(I) N-heterocyclic carbene complexes Ag(I)-NHCs were synthesized according to the Lin?s Ag2O method. To a solution of 1 mmol of NHC precursors (1,3-disubstituted imidazolinium chloride salts) in 5 mL of DCM, 0.5 mmol of Ag2O was added and the mixture was stirred at room temperature for 18 h. Later the reaction mixture was filtered through a celite and concentrated under vacuo to obtain the desired Ag(I)-NHC catalysts as a white crystalline solids.

141556-45-8, As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Article; Thirukovela, Narasimha Swamy; Balaboina, Ramesh; Kankala, Shravankumar; Vadde, Ravindhar; Vasam, Chandra Sekhar; Tetrahedron; vol. 75; 18; (2019); p. 2637 – 2641;,
Chiral Catalysts
Chiral catalysts – SlideShare

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.141556-45-8,1,3-Dimesityl-1H-imidazol-3-ium chloride,as a common compound, the synthetic route is as follows.

Tris [4- (pyridin-4-yl) phenyl] amine compound (47.6 mg, 0.10 mmol)1,3-bis (2,4,6-trimethylphenyl) imidazole chloride(IMes. HCl) (102.1 mg, 0.30 mmol),PdCl2 (53.2 mg, 0.30 mmol)And potassium carbonate (41.5 mg, 0.30 mmol) were added to a 25 mL single neck flask,Tetrahydrofuran (5 mL) was then added,The reaction was stirred at 75 C for 14 h under argon atmosphere.Stop the reaction,Cool to room temperature,concentrate,Thin layer chromatography to give compound II,Yield 50%., 141556-45-8

As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Patent; Shangqiu Normal University; Wang Tao; Xu Kai; Liu Lantao; Zhao Wenxian; Liu Shuang; Li Feng; Meng Tuanjie; Xie Huanping; (12 pag.)CN105131044; (2017); B;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

V-heterocyclic carbenes were synthesized from their corresponding imidazolium or imidazolinium salts (see Table 1 ). About 0.8 eq. of potassium tert- butoxide (8.9 mg) and 1 eq. of a 1 , 3-disubstituted imidazolium salt (Table 1 , entries 1 – 5) or 1 , 3-disubstituted imidazolinium salt (Table 1 , entry 7) was dissolved in 2 ml_ of tetrahydrofuran (THF). The reaction was stirred for 1 h under argon protection at ambient temperature. The solvent was then removed in vacuo. The resulting carbene was used without further purification and was characterized by 1H NMR and mass spectrometry.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Patent; SOUTHERN ILLINOIS UNIVERSITY CARBONDALE; WO2008/70756; (2008); A2;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

General procedure: Under an N2 atmosphere, the mixture of imidazolium salts 1 (1.1 mmol), benzoxazole or benzothiazole (2.0 mmol), PdCl2 (1.0 mmol) and K2CO3 (1.1 mmol) was stirred in anhydrous THF (10 mL) under reflux for 16 h. After cooling, filtration and evaporation,the residue was purified by preparative TLC on silica gelplates eluting with CH2Cl2 to afford the corresponding N-heterocyclic carbene-palladium(II) complexes 3a-d.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Wang, Tao; Xie, Huanping; Liu, Lantao; Zhao, Wen-Xian; Journal of Organometallic Chemistry; vol. 804; (2016); p. 73 – 79;,
Chiral Catalysts
Chiral catalysts – SlideShare

1,3-Dimesityl-1H-imidazol-3-ium chloride, cas is 141556-45-8, it is a common heterocyclic compound, the chiral-catalyst compound, its synthesis route is as follows.,141556-45-8

To anhydrous 1,4-dioxane (20 mL), [Pd(acac)2] (1 g, 3.3 mmol,1 equiv) and IMes*HCl (1.43 g, 3.7 mmol, 1.1 equiv) were added. The mixture was refluxed for 24 h. After the reaction, solvent was evaporated under vacuum. Diethyl ether was then added and stirred until no more solid was dissolved. The solution was filtered and diethyl ether was removed under vacuum. Yellow powder was washed with n-pentane and dried under vacuum. Yellow solids, yield:85%, 1H NMR (399.78 MHz, CDCl3) delta 7.08-6.94 (br,6H), 5.1 (s, 1H), 2.47-2.02 (br, 18H), 1.84-1.73 (6H), 13CNMR (100.53 MHz, CDCl3) delta 187.21, 183.16, 153.93,139.29, 137.60, 136.35, 135.01, 129.76, 128.90, 123.8,122.57, 99.68, 27.17, 25.61, 21.29, 18.93, 17.85.Synthesis of (IMes)Pd(tmhd)Cl. Yellow solids, yield:76%, 1H NMR (399.78 MHz, CDCl3) delta 7.09-6.96 (6H),5.50 (s, 1H), 2.40-2.31 (12H), 2.21-2.16 (6H), 1.04-0.95(18H), 13C NMR (100.53 MHz, CDCl3) delta 139.08, 136.64,135.40, 130.00, 128.74, 124.04, 90.65, 41.15-40.64, 29.07,28.51, 21.25, 18.99.

As the rapid development of chemical substances, we look forward to future research findings about 141556-45-8

Reference£º
Article; Lee, Dong Jin; Kim, Myungwoong; Kim, Chan Kyung; Lee, Ik Mo; Bulletin of the Korean Chemical Society; vol. 40; 7; (2019); p. 710 – 718;,
Chiral Catalysts
Chiral catalysts – SlideShare

141556-45-8, 1,3-Dimesityl-1H-imidazol-3-ium chloride is a chiral-catalyst compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: 0.340 g (1.00 mmol) of 1,3-bis(2,4,6-trimethylphenyl)imidazolium chloride was deprotonated by the addition of n-BuLi (1.00 mmol) in THF at -40C. The reaction mixture was allowed to stir for 30 min after which 0.390 g dimanganese decacarbonyl (1.00 mmol) was added. The reaction mixture turned a deep orange colour after the introduction of the metal complex and the reaction mixture was allowed to slowly warm up to room temperature. The solvent was removed in vacuo and purified via silica gel chromatography by eluting first with hexane and secondly with a hexane-DCM 1:1 mixture.

141556-45-8, As the paragraph descriping shows that 141556-45-8 is playing an increasingly important role.

Reference£º
Article; Fraser, Roan; van Sittert, Cornelia G.C.E.; van Rooyen, Petrus H.; Landman, Marile; Journal of Organometallic Chemistry; vol. 835; (2017); p. 60 – 69;,
Chiral Catalysts
Chiral catalysts – SlideShare