Category: 542-58-5

Electric Literature of C4H7ClO2. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 2-Chloroethyl acetate, is researched, Molecular C4H7ClO2, CAS is 542-58-5, about Dependence of vicinal H-H coupling constants in substituted ethanes on the potential function characteristics to internal rotation. Application to A2B2 PMR spectrum of nonsymmetrical 1,2-disubstituted ethanes.

Based on rotational averaging, a theory governing the change of the vicinal coupling parameters L and N in the A2B2 PMR spectra of nonsym. 1,2-disubstituted ethanes, as evidenced in the studies of substituent effect and solvent effect, has been developed in terms of the potential function characteristics to internal rotation about the C-C bond. By taking the average over the entire period of dihedral angle with respect to an appropriate potential function for internal rotation of the compound, a refined Karplus equation for the vicinal H-H coupling constant as a function of dihedral angle, J = A cosΦ2 + B cosΦ + C, could yield the expression for L/A and (or) N/A in terms of hyperbolic Bessel functions which describes an explicit functional dependence of L and (or) N on both the ethane barrier and the maximum dipole interaction potential between the 2 bonds C-X and C-Y. These expressions enable one to determine the phys. parameters related to internal rotation upon measurement of L and (or) N from NMR spectrum. The determined energy difference between rotamers for several 1,2-disubstituted ethanes were found in good agreement with the literature values. Solvent effect on the A2B2 PMR spectrum is discussed on the light of the theory. The NMR exptl. relation N ∓ 1/3 |L| = A was derived from the above expressions. This latter relation enables one to tell whether the trans or the gauche isomer is more stable for the given compound from measurement on N and L with respect to the neat sample or in the medium of various solvents, and it also enables one to evaluate the value of A for each given compound

Different reactions of this compound(2-Chloroethyl acetate)Electric Literature of C4H7ClO2 require different conditions, so the reaction conditions are very important.

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Shi, Jiaqi; Long, Tao; Ying, Rongrong; Wang, Lei; Zhu, Xin; Lin, Yusuo published the article 《Chemical oxidation of bis(2-chloroethyl) ether in the Fenton process: Kinetics, pathways and toxicity assessment》. Keywords: kinetics oxidation bis chloroethyl ether Fenton process toxicity; Bis(2-chloroethyl) ether; Fenton; Oxidation pathway; Toxicity change.They researched the compound: 2-Chloroethyl acetate( cas:542-58-5 ).Name: 2-Chloroethyl acetate. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:542-58-5) here.

Bis(2-chloroethyl) ether (BCEE) is a common chem. material and a frequently detected contaminant in groundwater. It has a strong toxicity and some other chems. such as poly(vinyl chloride-co-iso-Bu vinyl ether) contain similar chloroaliph. ether structure. So the effective degradation method and transformation pathways for BCEE need to be learned. The present study compared the degradation rate of BCEE by Fenton′s reagent and other common oxidation methods, and optimized the reaction conditions. Oxidation intermediates and pathways were also proposed and toxicities of the intermediates were investigated. Results showed that Fenton was highly effective to degrade BCEE. pH, Fe2+ and H2O2 concentration all affected the oxidation rate, among which Fe2+ was the most significant variable. A total of twelve chlorinated intermediates were detected. Three main reaction pathways involved cleavage of the ether bond, hydroxyl substitution for hydrogen, and radical coupling. The pathways could be well interpreted and supported by theor. calculations The reaction mixture showed a decreasing trend in TOC concentration and toxicity until totally harmless to Vibrio fischeri after 15 min, but it was noteworthy that toxicities of some dimeric intermediates were stronger than BCEE by calculation

Different reactions of this compound(2-Chloroethyl acetate)Name: 2-Chloroethyl acetate require different conditions, so the reaction conditions are very important.

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The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 2-Chloroethyl acetate( cas:542-58-5 ) is researched.Formula: C4H7ClO2.Musavirov, R. S.; Mullakhmetova, Z. F.; Nedogrei, E. P.; Kantor, E. A.; Rakhmankulov, D. L.; Paushkin, Ya. M. published the article 《Reaction of cyclic ketals of ethylene glycol with hydrogen chloride》 about this compound( cas:542-58-5 ) in Doklady Akademii Nauk SSSR. Keywords: ethanediol cyclic ketal ring cleavage; hydrogen chloride reaction cyclic ketal; chloroethyl carboxylate. Let’s learn more about this compound (cas:542-58-5).

I [R = R1 = Me; RR1 = (CH2)4, (CH2)5] were saturated with dry HCl and then heated 2 h at 150° to give AcOCH2CH2Cl, R2(CH2)4CO2CH2CH2Cl (R2 = 1-cyclopentenyl), and R3(CH2)5CO2CH2CH2Cl (R3 = 1-cyclohexenyl), resp., in low yields.

The article 《Reaction of cyclic ketals of ethylene glycol with hydrogen chloride》 also mentions many details about this compound(542-58-5)Formula: C4H7ClO2, you can pay attention to it, because details determine success or failure

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Halo-l,4-dioxanes and their derivatives. II. Thermal rearrangement and reactions of 2,3-dichloro-l,4-dioxane》. Authors are Cort, L.A.; Francis, N. R..The article about the compound:2-Chloroethyl acetatecas:542-58-5,SMILESS:CC(OCCCl)=O).Formula: C4H7ClO2. Through the article, more information about this compound (cas:542-58-5) is conveyed.

cf. CA 55, 546g. Thermal rearrangement of 2,3-dichloro-1,4-dioxane (I) to give both 1,2-dichloroethane and glyoxal has been detected, but the extent of this overall rearrangement is very small. Further eases are reported where the dichlorodioxane fails to yield substitution derivatives Reaction with acetanilide, with o-hydroxyacetanilide, and with acetamide yields in each case some 2-chloroethyl acetate.

The article 《Halo-l,4-dioxanes and their derivatives. II. Thermal rearrangement and reactions of 2,3-dichloro-l,4-dioxane》 also mentions many details about this compound(542-58-5)Formula: C4H7ClO2, you can pay attention to it, because details determine success or failure

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Product Details of 542-58-5. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 2-Chloroethyl acetate, is researched, Molecular C4H7ClO2, CAS is 542-58-5, about Studies on acute oral toxicity of homologous ω-chloroalcohols and ω-chloroalkyl acetates. Author is Weisbrod, D.; Stephan, Ursula; Fischer, G. W..

Acute oral LD50s of the title compounds for mice were: chloroethanol [107-07-3] 150, 3-chloropropan-1-ol [627-30-5] 2300, 4-chlorobutan-1-ol [928-51-8] 990, 2-chloroethyl acetate [542-58-5] 250, 3-chloropropan-1-yl acetate [628-09-1] 5290, 4-chlorobutan-1-yl acetate [6962-92-1] 1700, and bis(4-chlorobutan-1-yl)ether [39616-49-4] 1210 mg/kg. The acute oral toxicity of these homologous ω-chloroalcs., Cl(CH2)nOH and their acetyl derivatives Cl(CH2)nOCOCH3 (n = 2-4), decreases drastically on changing from n = 2 to n = 3 to increase again for n = 4. The possible reasons for this behavior are discussed.

The article 《Studies on acute oral toxicity of homologous ω-chloroalcohols and ω-chloroalkyl acetates》 also mentions many details about this compound(542-58-5)Product Details of 542-58-5, you can pay attention to it, because details determine success or failure

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Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2-Chloroethyl acetate, is researched, Molecular C4H7ClO2, CAS is 542-58-5, about Syntheses and reactions of functional polymers. LXXXII. Aminolyses of alkyl acetates containing electron-withdrawing substituents in leaving groups.COA of Formula: C4H7ClO2.

The aminolysis of alkyl acetates AcOCH2R (R = Me, CH2Cl, CH2CN, CCl3) was examined The relative rates in DMF were 1, 37, 87, 2700, resp. Similar relative reactivities were observed in the reaction with H2N(CH2)2NH2 in DMF or with H2N (CH2)2OH in dioxane. The ρ values in all cases were > 3 in Taft’s quantum log (k/k0) = ρ * σ*. A linear relation of log k/k0 with νCO was observed Inductive effects played an important role in the activation of the alkyl acetates. The mechanism was also discussed.

After consulting a lot of data, we found that this compound(542-58-5)COA of Formula: C4H7ClO2 can be used in many types of reactions. And in most cases, this compound has more advantages.

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Cleavage of cyclic acetals by acyl halides. Reaction mechanism》. Authors are Atavin, A. S.; Trofimov, B. A.; Orlova, S. E.; Keiko, V. V..The article about the compound:2-Chloroethyl acetatecas:542-58-5,SMILESS:CC(OCCCl)=O).Application of 542-58-5. Through the article, more information about this compound (cas:542-58-5) is conveyed.

A mixture of 25.5 g. 2,4-dimethyl-1,3-dioxolane (36% trans, 64% cis), 0.1 g. ZnCl2, and 19.6 g. AcC1 (I) was held at 50° 3 hrs. and distilled to yielding, in addition to starting materials, 2.2 g. resinous residue, and two fractions corresponding to β-chloroisopropyl acetate (II) and propylene glycol diacetate (III). To remove traces of an intermediate α-chloro ether, III was extracted with water, dried with Na2SO4, and redistilled The yield, b.p., n20D and d20 were resp.: II, 32.5%, b33 66-7°, 1.4223, 1.0914; III, 18.3%, b25 90-3°, 1.4170, 1.0559. Analogously, reaction of I with 2-methyl-1,3-dioxolane (IV) yielded β-chloroethyl acetate (V) and ethylene glycol diacetate (VI). Reaction of I with 2,4-dimethyl-1,3-dioxane yielded 1,3-butanediol diacetate (VII) and a mixture (VIII) of the acetates of 1-chloro-3-butanol and 3-chloro-1-butanol. The b.p., n20D and d20 were resp.: V, b10 41°, 1.4220, 1.1472; VI, b20 87°, 1.4170, 1.1063; VII, b7 82°, 1.4202, 1.0399; VIII b7, 57°, 1.4299, 1.0666. A mixture of 22 g. IV with 0.2 g. AlCl3 and 46.2 g. BzBr was agitated 11 hrs. at 70-100°, and vacuum distilled One fraction (b4 120-30°) afforded, after removal of BzOH crystals and redistillation, 14.5 g. β-bromoethyl benzoate (IX). A second fraction (b2 180-95°), after recrystallization from EtOH, afforded 13 g. of ethylene glycol dibenzoate, m. 69°, b2 180-3°. The tarry distillation residue weighed 8.9 g. Similarly, a mixture of 36.5 g. diisopropyl acetal, 19.6 g. I, and 0.15 g. ZnCl2 on fractionation yielded 8.2 g. of isopropyl acetate (X), along with iso-PrCl and a residue (13.7 g.). The b.p., n20D, and d20 of IX and X are, resp.: IX, b2 102-5°, 1.5478, 1.4308; X, b720 85-6°, 1.3760, 0.8689. To investigate proposed mechanisms involving chloro ether and ester intermediates, some of these possible intermediates were independently prepared Saturation of 10 g. vinyl acetate with HCl at 3-5°, and distillation of the product yielded 86% α-chloroethyl acetate, b718 115-18°, n20D 1.4055, d20 1.1016. I (39 g.) was added over 2.5 hrs. to an agitated mixture of 44 g. monovinyl ether of ethylene glycol in 100 ml. Et3N. After separation of the amine hydrochloride distillation yielded 70.4% vinyl β-acetoxyethyl ether (XI), b35 64-6°, n20D 1.4259, d20 1.0060. Saturation of XI with dry HCl at 0° and fractionation yielded 72% 1-(α-chloroethoxy)-2-acetoxyethane (XII), b15 84°, n20D 1.4348, d20 1.1281. When 16 g. XII was treated with 0.1 g. ZnCl2 and heated to 37°, the mixture evolved HCl and darkened. Fractionation yielded 6 g. V, 2.6 g. VI, and 1.9 g. tar. The decomposition of XII is consistent with the hypothesis that XII is a reaction intermediate in the reaction of I with IV. Since these reactions also proceed non-catalytically the catalyst role is regarded as accelerating the removal of the halogen from the acyl chloride (e.g. to form Ac+[ZnCl3-]), with subsequent nucleophilic attack by the acetal O on the pos. charged acylium carbon. If the resulting complex expels a proton, a vinyl ether is formed, whose polymerization explains the tars.

After consulting a lot of data, we found that this compound(542-58-5)Application of 542-58-5 can be used in many types of reactions. And in most cases, this compound has more advantages.

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Preparation and hydrolysis of esters derived from the substituted aliphatic alcohols》. Authors are Drushel, W. A.; Bancroft, G. R..The article about the compound:2-Chloroethyl acetatecas:542-58-5,SMILESS:CC(OCCCl)=O).Product Details of 542-58-5. Through the article, more information about this compound (cas:542-58-5) is conveyed.

AcOCHCIMe, AcOCHMeOEt, and EtCO2CHMeCl, which were prepared by methods previously recorded in the chem. literature, were all immediately decomposed when dissolved in 0.1 N HCl. Their reaction velocities are, therefore, not measurable. AcH formed one of the hydrolysis products in the case of all 3 esters. AcOCH2CH2OH (A), b. 187-9°, was prepared by heating under reflux equimol, amounts of (CH2OH)2 and glacial AcOH together with twice the theoretical amount of anhydrous CuSO4. AcOCH2CH2OMe (B). b. 144-5°, was formed by treating the corresponding alc. with AcCl. AcOCH2CH2OEt (C), b. 157-8°, was prepared from the corresponding ale. (which was formed by Polomaa’s method (Ber. 35, 3300(1902)) or by heating CH2BrCH2OAc (D) with an equimol. amount of EtONa. CH2ClCH2OAc (E), b. 143-5° was obtained by Henry’s method (Ber. 7, 70(1874)). A mixture of equimol. quantities of (CH2Br)2 and fused AcOK when heated on the H2O bath for 18 hrs. gave rise not to (A) but to (CH2OAc)2. Hydrolysis of (A), (B). (C), (D), (E) by means of 0.1 N HCl was effected at 25, 35 and 45°, and the velocity constants and temperature coefficients determined The subsitution of -OH, -OR, or halogen in place of the β-H hi the alkyl radical of AcOEt, causes retardation in the rate of hydrolysis. The -OH, -OEt, and Cl groups all produce practically the same degree of retardation. EtO causes a slightly greater retardation than does the OMe group, Br- causes less of ft retardation than does the Cl-radical. The temperature coefficients of the above esters varied from 2.3 to a.j for an increase of 10°. The substitution of Br bad ft lowering effect upon the temp, coefficient

After consulting a lot of data, we found that this compound(542-58-5)Product Details of 542-58-5 can be used in many types of reactions. And in most cases, this compound has more advantages.

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Szymanowski, J.; Kusz, P.; Dziwinski, E.; Latocha, C. published an article about the compound: 2-Chloroethyl acetate( cas:542-58-5,SMILESS:CC(OCCCl)=O ).Formula: C4H7ClO2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:542-58-5) through the article.

Oligooxyethylene glycol mono-(4-alkylphenyl) ethers were degraded with an excess of acetyl chloride in the presence of anhydrous FeCl3 at 150° in 0.5 h. Oligooxyethylene chains are degraded mainly to 2-chloroethyl acetate, while unidentified resins are mainly formed from alkylphenyl groups. 4-(1,1,3,3-Tetra-methylbutyll)phenyl-3,6-dimethyl-1-cyclohexenyl ether is the main low-molar-mass component formed from alkylphenyl groups. The contents of the compounds obtained by degradation of oligooxyethylene chains can be precisely determined and used to calculate the average degree of ethoxylation. Good agreement is observed between the average degree of ethoxylation determined by direct chromatog. anal. and after degradation

After consulting a lot of data, we found that this compound(542-58-5)Formula: C4H7ClO2 can be used in many types of reactions. And in most cases, this compound has more advantages.

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In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and Study of Some New Histidine Derivatives, published in 2014-04-30, which mentions a compound: 542-58-5, mainly applied to Schiff base imidazole oxazole preparation, Synthetic Route of C4H7ClO2.

The oxazole I was prepared by reaction of histidine with acetic anhydride, which on treatment with thiosemicarbazide afforded ((4-(1H-imidazol-4-ylmethyl)-2-methyl-4,5-dihydro-1,3-oxazol-5-ylidene)amino)thiourea (Schiff base) . The desired histidine derivatives, e.g., II, were synthesized from Schiff base and oxazole I via various organic reactions.

Although many compounds look similar to this compound(542-58-5)Synthetic Route of C4H7ClO2, numerous studies have shown that this compound(SMILES:CC(OCCCl)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

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