Discovery of 2,2-Biphenol

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Synthetic Route of 1806-29-7. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 1806-29-7, Name is 2,2-Biphenol. In a document type is Article, introducing its new discovery.

The Williamson reaction between (R,S)-[1,1′-binaphthyl]-2,2′-diol 1 and (R,S)-2,2′-bis (bromomethyl)-1,1′ binaphthyl 2 in acetone, gave the diastereoisomeric dioxacyclophanes (R*,S*)-3a and (R*,R*)-3b in high yield.

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Reference:
Chiral Catalysts,
Chiral catalysts – SlideShare