The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.23190-16-1, Name is (1R,2S)-(?)-2-Amino-1,2-diphenylethanol, molecular formula is C6H5CH(NH2)CH(C6H5)OH. In a Article£¬once mentioned of 23190-16-1, name: (1R,2S)-(?)-2-Amino-1,2-diphenylethanol
Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono-and diketones to nitroalkenes
Novel bifunctional chiral squaramide-amine organocatalysts have been developed by rational combination of pyrrolidine and a cinchona alkaloid. The catalysts promoted the enantioselective Michael addition of both mono-and diketones to a broad range of nitroalkenes providing the corresponding products in moderate to high yields with excellent enantioselectivities and diastereoselectivities (up to 96% yield, 96% ee, 98:2 dr) under mild conditions. These results demonstrate that the assembly of two chiral privileged skeletons, pyrrolidine and cinchonine with a squaramide linker is a useful strategy to reach a wider substrate scope, high reaction efficiency and enantioselectivity. The match of the chiralities between two backbones embedded in the catalysts is also critical for improving enantioselectivity. ARKAT-USA, Inc.
The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 23190-16-1 is helpful to your research., name: (1R,2S)-(?)-2-Amino-1,2-diphenylethanol
Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare