Muneyuki, Ryonosuke; Oka, Tatsushi; Morihara, Kazuyuki published an article about the compound: H-Leu-NH2.HCl( cas:10466-61-2,SMILESS:N[C@@H](CC(C)C)C(N)=O.[H]Cl ).Related Products of 10466-61-2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:10466-61-2) through the article.
Water-soluble poly(ethylene glycol) esters PhCH2O2C-Phe-(OCH2CH2)4OH and PhCH2O2C-Val-Tyr-(OCH2CH2)nOH (n = 9.1, 22.7) were treated with H-Leu-NH2 in the presence of α-chymotrypsin to give the corresponding peptide amides, which precipitate as insoluble products. Immobilized proteases were used in the conversion of porcine insulin into human insulin via semisynthetic methods; the key step was the coupling of porcine des-alaB30-insulin with H-Thr-OCMe3. Achromobacter Protease I immobilized on poly(glutamic acid) exhibited high activity.
Different reactions of this compound(H-Leu-NH2.HCl)Related Products of 10466-61-2 require different conditions, so the reaction conditions are very important.