The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Action of thionyl chloride on 2-methyl- and 2-ethyl-1,3-dioxolane-2-carboxylic acid》. Authors are Sneeden, R. P. A..The article about the compound:2-Chloroethyl acetatecas:542-58-5,SMILESS:CC(OCCCl)=O).Synthetic Route of C4H7ClO2. Through the article, more information about this compound (cas:542-58-5) is conveyed.
cf. Vogel and Schinz, C.A. 44, 5315e. SOCl2 reacted with 2-methyl- (I) and 2-ethyl-1,3-dioxolane-2-carboxylic acids (II) to yield the 2-chloroethyl acetate III and propionate (IV), resp. Addition of 7.65 g. ethylene ketal of Et pyruvate (with cooling) to 4.05 g. KOH in 5.05 ml. H2O, treatment with 7.0 g. concentrated HCl, and continuous extraction with ether gave I, b14 127-30° n19D 1.4440. I (12.8 g.) kept overnight in 7.5 ml. SOCl2 and distilled gave III, b. 143°, n18D 1.4250. Similar treatment of ethylene ketal of Et α-oxobutyrate gave II, b34 160-5°, n17.5D 1.4530. SOCl2 converted II to IV, b60 80-5°, n14D 1.4320.
This literature about this compound(542-58-5)Synthetic Route of C4H7ClO2has given us a lot of inspiration, and I hope that the research on this compound(2-Chloroethyl acetate) can be further advanced. Maybe we can get more compounds in a similar way.