Related Products of 23190-16-1. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 23190-16-1, Name is (1R,2S)-(−)-2-Amino-1,2-diphenylethanol
Chirality switching was induced by solvents in the enantioseparation of 2-hydroxy-4-phenylbutyric acid (HPBA) via diastereomeric salt formation with an enantiopure aminoalcohol. The (S)-salt was crystallized from butanol solutions and the (R)-salt was obtained from aqueous solutions. It was found from crystallographic analysis of the salts that solvent inclusion changed the solubility of both salts. In particular, the (R)-salt afforded multiple pseudo-polymorphic hydrated crystals. Successive crystallization from two different solvents efficiently afforded both pure diastereomeric salts.
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Reference:
Chiral Catalysts,
Chiral catalysts – SlideShare