Application of 250285-32-6. Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 250285-32-6, Name is 1,3-Bis(2,6-diisopropylphenyl)imidazolium chloride
NHC-Pd(II)-azole complexes catalyzed Suzuki?Miyaura cross-coupling of sterically hindered aryl chlorides with arylboronic acids
In order to synthesize hindered biaryls efficiently, a series of NHC-Pd(II)-azole complexes bearing sterically hindered ligands were synthesized and characterized. The steric environment effect as well as the electronic effect of the azole ligands has been assessed. All these complexes were applied in the Suzuki?Miyaura cross-coupling reaction of sterically hindered aryl chlorides with low catalysts loadings (0.1 mol %) under mild conditions in air and good to excellent isolated yields of sterically hindered biaryls were obtained.
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Reference£º
Chiral Catalysts,
Chiral catalysts – SlideShare