Synthetic Route of 33100-27-5. Let’s face it, organic chemistry can seem difficult to learn. Especially from a beginner’s point of view. Like 33100-27-5, Name is 1,4,7,10,13-Pentaoxacyclopentadecane. In a document type is Article, introducing its new discovery.
Candida albicans produces various quorum sensing molecules (QSMs) which are involved in biological processes, e.g. morphological changes or biofilm formation. Thus, a sensitive and selective electrochemical assay was developed for determination of tryptophol as one of the most important QSMs. Preparation, characterization, and testing the electrocatalytic activity of prepared sensors with various sensing elements and nanomaterials were investigated. In addition, the effects of supporting electrolytes, pH of buffer solutions, scan rate, and possible interferences on the response of tryptophol’s sensor were studied. Eventually, improving the sensitivity and selectivity were achieved using a combination of 12-crwon-4-ether and MWCNTs (10% w/w for each). With the developed electrochemical sensor, the linear response was observed from 10 mug/ml to 110 mug/ml with the detection limit of 1 mug/ml and regression coefficient of 0.998. Consequently, the method was successfully applied for the detection of tryptophol in the fungal culture.
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Reference：
Chiral Catalysts,
Chiral catalysts – SlideShare