Let¡¯s face it, organic chemistry can seem difficult to learn, Computed Properties of C6H14ClNO5, Especially from a beginner¡¯s point of view. Like 5505-63-5, Name is (2S,3R,4S,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal hydrochloride, molecular formula is C21H19O2P, belongs to pyridazines compound. In a document, author is Zhang, Jiayan, introducing its new discovery.
Enantioselective dearomative [3 + 2] annulation of 3-hydroxy chromanones with azonaphthalenes was realized using a chiral squaramide-tertiary amine as a catalyst. A large variety of chromanone fused indolines were obtained in moderate to good yields (up to 93%) with generally good enantioselectivities (up to 95% ee). The absolute configuration of one of the products was assigned by an X-ray crystal structural analysis, and a plausible reaction mechanism was proposed. Afterwards, two arylated derivatives were prepared by the Suzuki-Miyaura coupling of one of the products with aryl boronic acids.
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Reference:
Chiral Catalysts,
,Chiral catalysts – SlideShare